Intermachine differences in DXA measurements vary by skeletal site, and impact the assessment of low bone density in children.

ABSTRACT:

Background

Bone mineral content (BMC) and areal-bone mineral density (aBMD) measurements of the lumbar spine (LS) and whole body less head (WBLH) by dual energy X-ray absorptiometry (DXA) are recommended for bone health assessment in children. Intermachine differences were not considered previously in formulating these recommendations.

Methodology

DXA measurements of the LS, WBLH, total hip, femoral neck and distal 1/3 radius from the Bone Mineral Density in Childhood Study were examined. Healthy children, ages 6 to 16 years, from five clinical centers participated. The same spine, whole body, and femur phantoms were measured on each Center's DXA machine. Percentage of individuals with low BMC or aBMD (Z-score < -1.5) was determined. Clinical center differences were evaluate

SUBMITTER: Zemel BS 

PROVIDER: S-EPMC7680379 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature