Liver resection for hepatocellular carcinoma in patients with clinically significant portal hypertension.

ABSTRACT:

Background & aims

Liver resection (LR) in patients with hepatocellular carcinoma (HCC) and clinically significant portal hypertension (CSPH) defined as a hepatic venous pressure gradient (HVPG) ≥10 mmHg is not encouraged. Here, we reappraised the outcomes of patients with cirrhosis and CSPH who underwent LR for HCC in highly specialised liver centres.

Methods

This was a retrospective multicentre study from 1999 to 2019. Predictors for postoperative liver decompensation and textbook outcomes were identified.

Results

In total, 79 patients with a median age of 65 years were included. The Child-Pugh grade was A in 99% of patients, and the median model for end-stage liver disease (MELD) score was 8. The median HVPG was 12 mmHg. Major hepatectomies and laparoscopies were pe

SUBMITTER: Azoulay D 

PROVIDER: S-EPMC7689549 | biostudies-literature | 2021 Feb

REPOSITORIES: biostudies-literature