Evaluation of rapid antigen detection kit from the WHO Emergency Use List for detecting SARS-CoV-2.

ABSTRACT:

Background

Currently, there are two rapid antigen detection (RAD) kits from the WHO Emergency Use List for detecting SARS-CoV-2.

Objective

The Panbio COVID-19 Ag Rapid Test Device was selected to evaluate the performance for detecting SARS-CoV-2.

Study design

Analytical sensitivity for the detection of SARS-CoV-2 virus was determined by limit of detection (LOD) using RT-PCR as a reference method. Clinical sensitivity was evaluated by using respiratory specimens collected from confirmed COVID-19 patients.

Results

The LOD results showed that the RAD kit was 100 fold less sensitive than RT-PCR. Clinical sensitivity of the RAD kit was 68.6 % for detecting specimens from COVID-19 patients.

Conclusions

The RAD kit evaluated in the present study shared similar

SUBMITTER: Mak GCK 

PROVIDER: S-EPMC7716730 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature