Association of the CHA₂D(S₂)-VASc Score and Its Components With Overt and Silent Ischemic Brain Lesions in Patients With Atrial Fibrillation.

ABSTRACT: Background: Silent and overt ischemic brain lesions are common and associated with adverse outcome. Whether the CHA₂DS₂-VASc score and its components predict magnetic resonance imaging (MRI)-detected ischemic silent and overt brain lesions in patients with atrial fibrillation (AF) is unclear. Methods: In this cross-sectional analysis, patients with AF were enrolled in a multicenter cohort study in Switzerland. Outcomes were clinically overt, silent [in the absence of a history of stroke/transient ischemic attack (TIA)] and any MRI-detected ischemic brain lesions. Logistic regression analyses were performed to assess the relationship of the CHA₂DS₂-VASc score and its components with ischemic brain lesions. An adapted CHA₂D

SUBMITTER: Steiner F 

PROVIDER: S-EPMC7835704 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature