Ontology highlight
ABSTRACT:
SUBMITTER: Oluwayiose OA
PROVIDER: S-EPMC7864951 | biostudies-literature | 2021 Feb
REPOSITORIES: biostudies-literature
Scientific reports 20210205 1
Parental age at time of offspring conception is increasing in developed countries. Advanced male age is associated with decreased reproductive success and increased risk of adverse neurodevelopmental outcomes in offspring. Mechanisms for these male age effects remain unclear, but changes in sperm DNA methylation over time is one potential explanation. We assessed genome-wide methylation of sperm DNA from 47 semen samples collected from male participants of couples seeking infertility treatment. ...[more]