Prevalence and risk analysis of mobile colistin resistance and extended-spectrum <i>β</i>-lactamase genes carriage in pet dogs and their owners: a population based cross-sectional study.

ABSTRACT: Mobile colistin resistance gene mcr-1 and extended-spectrum β-lactamase gene bla _CTX-M are highly prevalent in human - and pet-derived bacteria. Isolation of identical strains of mcr-1-positive Escherichia coli (MCRPEC) or bla _CTX-M-positive E. coli (CTX-MPEC) from pets and humans highlighted the potential for co-colonization of antibiotic-resistant bacteria which can be a risk for dissemination of resistance genes. In this study, the prevalence of mcr-1 and bla _CTX-M carriage from rectal swabs in 299 families (dogs and their owners) were 2.7 and 5.3%, respectively. We identified a significant association of mcr-1 carriage between dogs and their owners. Whilst antibiotic use in the previo

SUBMITTER: Lei L 

PROVIDER: S-EPMC7889244 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature