Ambient Particle Components and Newborn Blood Pressure in Project Viva.

ABSTRACT: Background Both elemental metals and particulate air pollution have been reported to influence adult blood pressure (BP). The aim of this study is to examine which elemental components of particle mass with diameter ≤2.5 μm (PM_2.5) are responsible for previously reported associations between PM_2.5 and neonatal BP. Methods and Results We studied 1131 mother-infant pairs in Project Viva, a Boston-area prebirth cohort. We measured systolic BP (SBP) and diastolic BP (DBP) at a mean age of 30 hours. We calculated average exposures during the 2 to 7 days before birth for the PM_2.5 components-aluminum, arsenic, bromine, sulfur, copper, iron, zinc, nickel, vanadium, titanium, magnesium, potassium, silicon, sodium, chlorine, calcium, and lead-measured at the Harvard

SUBMITTER: Zanobetti A 

PROVIDER: S-EPMC7955476 | biostudies-literature | 2021 Jan

REPOSITORIES: biostudies-literature