Predicting transcriptional responses to cold stress across plant species.

ABSTRACT: Although genome-sequence assemblies are available for a growing number of plant species, gene-expression responses to stimuli have been cataloged for only a subset of these species. Many genes show altered transcription patterns in response to abiotic stresses. However, orthologous genes in related species often exhibit different responses to a given stress. Accordingly, data on the regulation of gene expression in one species are not reliable predictors of orthologous gene responses in a related species. Here, we trained a supervised classification model to identify genes that transcriptionally respond to cold stress. A model trained with only features calculated directly from genome assemblies exhibited only modest decreases in performance relative to models trained by using genomic, chr

SUBMITTER: Meng X 

PROVIDER: S-EPMC7958178 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature