Prevalence of Brain Microbleeds in Alzheimer Disease: A Systematic Review and Meta-Analysis on the Influence of Neuroimaging Techniques.

ABSTRACT:

Background and purpose

The literature on the prevalence of Alzheimer disease-associated cerebral microbleeds assessed with MR imaging shows considerable heterogeneity in terms of imaging techniques and parameters. Our aim was to perform a meta-analysis of the role of imaging techniques, including image acquisition, field strength and scanner type, and clinical and demographic factors on the reported prevalence of microbleeds in Alzheimer disease.

Materials and methods

The prevalence of microbleeds was examined with respect to a priori-selected moderating variables via meta-analytic tools of literature reports.

Results

Fourteen unique studies providing 15 microbleed prevalence rates met the selection criteria for inclusion. The aggregate prevalence of microbleeds was 2

SUBMITTER: Sepehry AA 

PROVIDER: S-EPMC7959937 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature