Neurocognitive performance in alcohol use disorder using the NIH toolbox: Role of severity and sex differences.

ABSTRACT:

Aims

Sustained heavy alcohol consumption is associated with a range of neurocognitive deficits. Yet, past research centers on a severe profile of alcohol use disorder (AUD), with persons recruited from in-patient settings. The current project aims to compare neurocognitive performance between individuals seeking AUD outpatient treatment with healthy comparisons while considering the association between performance, disorder severity, and sex.

Methods

Enrollment included two matched groups (N = 125; 34 % female): 77 treatment-seeking individuals with AUD; 48 healthy comparison individuals with low drinking patterns. Neurocognitive performance on NIH Toolbox subtests measuring attention, inhibition, episodic memory, working memory, language, and processing speed were compared

SUBMITTER: Meredith LR 

PROVIDER: S-EPMC7972314 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature