The relationship of neurodevelopmental impairment to concurrent early childhood outcomes of extremely preterm infants.

ABSTRACT:

Objective

Determine how neurodevelopmental impairment (NDI) relates to concurrent outcomes for children born extremely preterm.

Study design

Retrospective cohort study children born 22 0/7-26 6/7 weeks' gestation at NICHD Neonatal Research Network hospitals. Outcomes were ascertained at 18-22 months' corrected age.

Result

Of 6562 children, 2618 (40%) died and 441 (7%) had no follow-up. Among the remaining 3483 children, 825 (24%), 1576 (45%), 657 (19%), and 425 (12%) had no, potential/mild, moderate, and severe NDI, respectively. Rehospitalization, respiratory medications, surgery, and medical support services were associated with greater NDI severity but affected >10% of children without NDI. Rehospitalization occurred in 40% of children with no NDI (mean (SD): 1.7 (

SUBMITTER: Rysavy MA 

PROVIDER: S-EPMC7985590 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature