A 3D analysis of growth trajectory and integration during early human prenatal facial growth.
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ABSTRACT:
SUBMITTER: Katsube M
PROVIDER: S-EPMC7994314 | biostudies-literature | 2021 Mar
REPOSITORIES: biostudies-literature
Publications
A 3D analysis of growth trajectory and integration during early human prenatal facial growth.
Katsube Motoki M Yamada Shigehito S Utsunomiya Natsuko N Yamaguchi Yutaka Y Takakuwa Tetsuya T Yamamoto Akira A Imai Hirohiko H Saito Atsushi A Vora Siddharth R SR Morimoto Naoki N
Scientific reports 20210325 1
Significant shape changes in the human facial skeleton occur in the early prenatal period, and understanding this process is critical for studying a myriad of congenital facial anomalies. However, quantifying and visualizing human fetal facial growth has been challenging. Here, we applied quantitative geometric morphometrics (GM) to high-resolution magnetic resonance images of human embryo and fetuses, to comprehensively analyze facial growth. We utilized non-linear growth estimation and GM meth ...[more]
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