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ABSTRACT: Background
COVID-19 disease can lead to severe functional impairments after discharge. We assessed the quality of life of invasively ventilated COVID-19 ARDS survivors.Methods
We carried out a prospective follow-up study of the patients admitted to the Intensive Care Units (ICUs) of a teaching hospital. Patients affected by COVID-19 ARDS who required invasive ventilation and were successfully discharged home were assessed through the telephone administration of validated tests. We explored survival, functional outcomes, return to work, quality of life, cognitive and psychological sequelae. The main variables of interest were the following: demographics, severity scores, laboratory values, comorbidities, schooling, working status, treatments received during ICU stay, complications, and psychological, cognitive, functional outcomes.Results
Out of 116 consecutive invasively ventilated patients, overall survival was 65/116 (56%) with no death occurring after hospital discharge. Forty-two patients were already discharged home with a median follow-up time of 61 (51-71) days after ICU discharge and 39 of them accepted to be interviewed. Only one patient (1/39) experienced cognitive decline. The vast majority of patients reported no difficulty in walking (32/35:82%), self-care (33/39:85%), and usual activities (30/39:78%). All patients were either malnourished (15/39:38%) or at risk for malnutrition (24/39:62%). Exertional dyspnea was present in 20/39 (51%) patients. 19/39 (49%) reported alterations in senses of smell and/or taste either before or after hospitalization.Conclusions
Invasively ventilated COVID-19 ARDS survivors have an overall good recovery at a 2-months follow-up which is better than what was previously reported in non-COVID-19 ARDS patients.
SUBMITTER: Monti G
PROVIDER: S-EPMC8014684 | biostudies-literature | 2021 Aug
REPOSITORIES: biostudies-literature
Monti Giacomo G Leggieri Carlo C Fominskiy Evgeny E Scandroglio Anna Mara AM Colombo Sergio S Tozzi Margherita M Moizo Elena E Mucci Milena M Crivellari Martina M Pieri Marina M Guzzo Francesca F Piemontese Simona S De Lorenzo Rebecca R Da Prat Valentina V Fedrizzi Monica M Faustini Carolina C Di Piazza Martina M Conte Francesca F Lembo Rosalba R Esposito Antonio A Dagna Lorenzo L Landoni Giovanni G Zangrillo Alberto A
Acta anaesthesiologica Scandinavica 20210315 7
<h4>Background</h4>COVID-19 disease can lead to severe functional impairments after discharge. We assessed the quality of life of invasively ventilated COVID-19 ARDS survivors.<h4>Methods</h4>We carried out a prospective follow-up study of the patients admitted to the Intensive Care Units (ICUs) of a teaching hospital. Patients affected by COVID-19 ARDS who required invasive ventilation and were successfully discharged home were assessed through the telephone administration of validated tests. W ...[more]