The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis.

ABSTRACT:

Background

To determine whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, the cause of COVID-19 disease) exposure in pregnancy, compared to non-exposure, is associated with infection-related obstetric morbidity.

Methods

We conducted a multicentre prospective study in pregnancy based on a universal antenatal screening program for SARS-CoV-2 infection. Throughout Spain 45 hospitals tested all women at admission on delivery ward using polymerase-chain-reaction (PCR) for COVID-19 since late March 2020. The cohort of positive mothers and the concurrent sample of negative mothers was followed up until 6-weeks post-partum. Multivariable logistic regression analysis, adjusting for known confounding variables, determined the adjusted odds ratio (aOR) with 95% confi

SUBMITTER: Martinez-Perez O 

PROVIDER: S-EPMC8016158 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature