Nomogram for predicting the overall survival of the patients with oesophageal signet ring cell carcinoma.

ABSTRACT:

Background

The purpose of this study was to explore the prognostic factors of oesophageal signet ring cell (SRC) carcinoma and to construct a nomogram for predicting the outcome of SRC carcinoma of oesophagus.

Methods

A total of 968 cases of oesophageal SRC carcinoma were extracted from the Surveillance, Epidemiology, and End Results (SEER) database between 2004 and 2016. Cases were divided into training cohort and validation cohort. Univariate and multivariable Cox analyses was performed to select the predictors of overall survival (OS for the nomogram. The performance of nomogram was validated with Harrell's concordance index (C-index), calibration curves and decision curve analysis (DCA).

Results

The 1- and 5-year OS in the training cohort were 0.446 and 0.146, res

SUBMITTER: Wang F 

PROVIDER: S-EPMC8024836 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature