Alcohol-impregnated caps and ambulatory central-line-associated bloodstream infections (CLABSIs): A randomized clinical trial.

ABSTRACT:

Objective

To evaluate the effect of 70% isopropyl alcohol-impregnated central venous catheter caps on ambulatory central-line-associated bloodstream infections (CLABSIs) in pediatric hematology-oncology patients.

Design

This study was a 24-month, cluster-randomized, 2 period, crossover clinical trial.

Setting

The study was conducted in 15 pediatric healthcare institutions, including 16 pediatric hematology-oncology clinics.

Participants

All patients with an external central line followed at 1 of the 16 hematology-oncology clinics.

Intervention

Usual ambulatory central-line care per each institution using 70% isopropyl alcohol-impregnated caps at home compared to usual ambulatory central-line care in each institution without using 70% isopropyl alcohol-im

SUBMITTER: Milstone AM 

PROVIDER: S-EPMC8039053 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature