Stress-elicited neural activity in young adults varies with childhood sexual abuse.

ABSTRACT:

Objective

Childhood physical and sexual abuse are stressful experiences that may alter the emotional response to future stressors. Stress-related emotional function is supported by brain regions that include the prefrontal cortex (PFC), hippocampus, and amygdala. The present study investigated whether childhood physical and sexual abuse are associated with stress-elicited brain activity in young adulthood.

Methods

Participants (N = 300; M_age = 20.0; 151 female) completed a psychosocial stress task during functional magnetic resonance imaging (fMRI). Measures of physical and sexual abuse were included in a linear mixed effects model to estimate the unique relationship each type of childhood abuse had with stress-elicited brain activity.

Results

Stress-elicit

SUBMITTER: Purcell JB 

PROVIDER: S-EPMC8044018 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature