CT radiomics to predict high-risk intraductal papillary mucinous neoplasms of the pancreas.

ABSTRACT:

Purpose

Intraductal papillary mucinous neoplasms (IPMNs) are radiographically visible precursor lesions of pancreatic cancer. Despite standard criteria for assessing risk, only 18% of cysts are malignant at resection. Thus, a large number of patients undergo unnecessary invasive surgery for benign disease. The ability to identify IPMNs with low or high risk of transforming into invasive cancer would optimize patient selection and improve surgical decision-making. The purpose of this study was to investigate quantitative CT imaging features as markers for objective assessment of IPMN risk.

Methods

This retrospective study analyzed pancreatic cyst and parenchyma regions extracted from CT scans in 103 patients to predict IPMN risk. Patients who underwent resection between 2005

SUBMITTER: Chakraborty J 

PROVIDER: S-EPMC8050835 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature