Walking Speed and Muscle Mass Estimated by the D₃-Creatine Dilution Method Are Important Components of Sarcopenia Associated With Incident Mobility Disability in Older Men: A Classification and Regression Tree Analysis.

ABSTRACT:

Objectives

It is unknown whether muscle mass measured by the D₃-creatine dilution method is a superior predictor of incident mobility disability than traditional components of sarcopenia definitions (including grip strength, walking speed, appendicular lean mass). The objective of this study was to determine the relative importance of strength; physical performance; and lean, fat, and muscle mass in predicting incident mobility disability in older men.

Design

Longitudinal cohort study of participants in the Osteoporotic Fractures in Men (MrOS) study.

Setting and participants

Muscle mass was assessed by D₃-creatine dilution in 1098 men (aged 83.7 ± 3.7 years). Participants also completed anthropomorphic measures, 6-m walking speed (m/s), grip stre

SUBMITTER: Zanker J 

PROVIDER: S-EPMC8057698 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature