Rtpca: an R package for differential thermal proximity coaggregation analysis.

ABSTRACT:

Summary

Rtpca is an R package implementing methods for inferring protein-protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages.

Availability and implementation

Rtpca is available from Bioconductor (https://bioconductor.org/packages/Rtpca).

Supplementary information

Supplementary data are available at Bioinformatics online.

SUBMITTER: Kurzawa N 

PROVIDER: S-EPMC8058776 | biostudies-literature | 2021 Apr

REPOSITORIES: biostudies-literature