Inflammation of the periodontium associates with risk of future cardiovascular events.

ABSTRACT:

Background

While growing evidence suggests a link between periodontal disease (PD) and cardiovascular disease (CVD), the independence of this association and the pathway remain unclear. Herein, we tested the hypotheses that: (1) inflammation of the periodontium (PD_inflammation ) predicts future CVD independently of disease risk factors shared between CVD and PD, and (2) the mechanism linking the two diseases involves heightened arterial inflammation.

Methods

¹⁸ F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸ F-FDG-PET/CT) imaging was performed in 304 individuals (median age 54 years; 42.4% male) largely for cancer screening; individuals without active cancer were included. PD_inflammation and arterial infla

SUBMITTER: Van Dyke TE 

PROVIDER: S-EPMC8080258 | biostudies-literature | 2021 Mar

REPOSITORIES: biostudies-literature