Gender differences in the prevalence of frailty in heart failure: A systematic review and meta-analysis.

ABSTRACT:

Objectives

This study quantitatively synthesized literature to identify gender differences in the prevalence of frailty in heart failure (HF).

Background

The intersection of frailty and HF continues to garner interest. Almost half of patients with HF are frail; however, gender differences in frailty in HF are poorly understood.

Methods

We performed a literature search to identify studies that reported prevalence of frailty by gender in HF. Random-effects meta-analysis was used to quantify the relative and absolute risk of frailty in women compared with men with HF, overall, and by Physical and Multidimensional Frailty measures. Meta-regression was performed to examine the influence of study age and functional class on relative risk in HF.

Results

Twenty-nine st

SUBMITTER: Davis MR 

PROVIDER: S-EPMC8107129 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature