Ontology highlight
ABSTRACT:
SUBMITTER: Fernandez Perez ER
PROVIDER: S-EPMC8181708 | biostudies-literature | 2021 Apr
REPOSITORIES: biostudies-literature
Fernández Pérez Evans R ER Crooks James L JL Swigris Jeffrey J JJ Solomon Joshua J JJ Mohning Michael P MP Huie Tristan J TJ Koslow Matthew M Lynch David A DA Groshong Steve D SD Fier Kaitlin K
ERJ open research 20210401 2
Hypersensitivity pneumonitis (HP) is an immunologically mediated form of lung disease resulting from inhalational exposure to any of a large variety of antigens. A subgroup of patients with HP develops pulmonary fibrosis (fibrotic HP; FHP), a significant cause of morbidity and mortality. This study will evaluate the safety and efficacy of the antifibrotic pirfenidone in treating FHP. This single-centre, randomised, double-blind, placebo-controlled trial is enrolling adults with FHP (ClinicalTria ...[more]