Effects of maternal stress and nutrient restriction during gestation on offspring neuroanatomy in humans.

ABSTRACT: Cognitive and mental health are major determinants of quality of life, allowing integration into society at all ages. Human epidemiological and animal studies indicate that in addition to genetic factors and lifestyle, prenatal environmental influences may program neuropsychiatric disorders in later life. While several human studies have examined the effects of prenatal stress and nutrient restriction on brain function and mental health in later life, potentially mediating effects of prenatal stress and nutrient restriction on offspring neuroanatomy in humans have been studied only in recent years. Based on neuroimaging and anatomical data, we comprehensively review the studies in this emerging field. We relate prenatal environmental influences to neuroanatomical abnormalities in the offsp

SUBMITTER: Franke K 

PROVIDER: S-EPMC8207653 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature