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Redefining the Origin and Evolution of Chromosomally Encoded blaCTX-M/KLU in the Context of a Revised Taxonomy of Genus Kluyvera.

ABSTRACT: Changes in Kluyvera taxonomy may clarify each species contribution for recruitment and dissemination of their relevant β-lactamases. The CTX-M-2 subgroup is linked to Kluyvera ascorbata, KLUC to Kluyvera cryocrescens, and CTX-M-25 to Kluyvera georgiana. The CTX-M-8 subgroup can be linked to Kluyvera genomospecies 3 and CTX-M-9 to Kluyvera genomospecies 2. Kluyvera sichuanensis and Kluyvera genomospecies 1 harbor new subgroups. The CTX-M-1 subgroup has a direct counterpart in an isolate proposed as a new genomospecies 5.

SUBMITTER: Rodriguez MM 

PROVIDER: S-EPMC8218679 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature

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Redefining the Origin and Evolution of Chromosomally Encoded <i>bla</i><sub>CTX-M/KLU</sub> in the Context of a Revised Taxonomy of Genus <i>Kluyvera</i>.

Rodríguez María Margarita MM   Power Pablo P   Naas Thierry T   Gutkind Gabriel G  

Antimicrobial agents and chemotherapy 20210617 7

Changes in <i>Kluyvera</i> taxonomy may clarify each species contribution for recruitment and dissemination of their relevant β-lactamases. The CTX-M-2 subgroup is linked to Kluyvera ascorbata, KLUC to Kluyvera cryocrescens, and CTX-M-25 to Kluyvera georgiana. The CTX-M-8 subgroup can be linked to <i>Kluyvera</i> genomospecies 3 and CTX-M-9 to <i>Kluyvera</i> genomospecies 2. Kluyvera sichuanensis and <i>Kluyvera</i> genomospecies 1 harbor new subgroups. The CTX-M-1 subgroup has a direct counter  ...[more]

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