Social isolation, inflammation, and cancer mortality from the National Health and Nutrition Examination Survey - a study of 3,360 women.

ABSTRACT:

Background

This study evaluates the role of social isolation on inflammation and cancer mortality among women.

Methods

Data were abstracted from the U.S. National Health and Nutrition Examination Survey from 1988 to 1994. The Social Network Index was used to assess participants' degree of social isolation. C-reactive protein and fibrinogen levels were included as markers of inflammation. We used the National Death Index to identify causes and dates of mortality. Chi-square and multivariable Cox regressions were employed for statistical analyses.

Results

Of 3360 women (median age: 54 years), the most isolated, very isolated, somewhat isolated, and not isolated comprised 14.5, 30.2, 37.1, and 18.2% of the sample, respectively. The most isolated participants were more li

SUBMITTER: Koh-Bell A 

PROVIDER: S-EPMC8252233 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature