Correlation Between ¹⁸F-FDG Uptake and Immune Cell Infiltration in Metastatic Brain Lesions.

ABSTRACT:

Background

The purpose of this study was to investigate the correlation between ¹⁸F-fluorodeoxyglucose (FDG) uptake and infiltrating immune cells in metastatic brain lesions.

Methods

This retrospective study included 34 patients with metastatic brain lesions who underwent brain ¹⁸F-FDG positron emission tomography (PET)/computed tomography (CT) followed by surgery. ¹⁸F-FDG uptake ratio was calculated by dividing the standardized uptake value (SUV) of the metastatic brain lesion by the contralateral normal white matter uptake value. We investigated the clinicopathological characteristics of the patients and analyzed the correlation between ¹⁸F-FDG uptake and infiltration of various immune cells. In addition, we evaluated immune-expr

SUBMITTER: An YS 

PROVIDER: S-EPMC8266210 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature