Phylogenetic analysis of HPAI H5N1 virus from duck swab specimens in Indonesia.

ABSTRACT:

Objective

A phylogenetic study was carried out on the avian influenza virus (AIV) isolated from a disease outbreak in Sidenreng Rappang Regency, South Sulawesi, Indonesia, in 2018.

Material and methods

Oropharyngeal swabs and organ samples were obtained from ducks that showed clinical symptoms: torticollis, fascial edema, neurological disorders, the corneas appear cloudy, and death occurs less than 1 day after symptoms appear. In this study, isolate A/duck/Sidenreng Rappang/07180110-11/2018 from duck was sequenced and characterized.

Results

It was found that each gene segment of the virus has the highest nucleotide homology to the Indonesian highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.2.1c. Multiple alignments of the sample Hemagglutinin (HA) gene with the

SUBMITTER: Mutisari D 

PROVIDER: S-EPMC8280988 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature