Phylogenetic analysis of congenital rubella virus from Indonesia: a case report.

ABSTRACT:

Background

Rubella is a common inherited infection resulting in congenital cataracts and a significant cause of permanent vision loss in developing countries. In 2016, Indonesia had the highest number of congenital rubella syndrome (CRS) cases globally. Here, we report the first genotype of the rubella virus extracted from the eye lens from a child with congenital cataracts due to CRS.

Case presentation

A female neonate was delivered by an elective caesarean delivery with normal birth weight at term from a 24-year-old mother in the rural setting. The baby presented with bilateral congenital cataracts, small-moderate secundum atrial septal defect, severe supravalvular pulmonary stenosis, and profound bilateral hearing loss. She also had microcephaly and splenomegaly. The pati

SUBMITTER: Herini ES 

PROVIDER: S-EPMC9745697 | biostudies-literature | 2022 Dec

REPOSITORIES: biostudies-literature