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Dataset Information

Assessment of Optimal Patient Selection for Endovascular Thrombectomy Beyond 6 Hours After Symptom Onset: A Pooled Analysis of the AURORA Database.


ABSTRACT:

Importance

The optimal imaging approach for identifying patients who may benefit from endovascular thrombectomy (EVT) beyond 6 hours after they were last known well is unclear. Six randomized clinical trials (RCTs) have evaluated the efficacy of EVT vs standard medical care among patients with ischemic stroke.

Objective

To assess the benefits of EVT among patients with 3 baseline imaging profiles using a pooled analysis of RCTs.

Data sources

The AURORA (Analysis of Pooled Data from Randomized Studies of Thrombectomy More Than 6 Hours After Last Known Well) Collaboration pooled patient-level data from the included clinical trials.

Study selection

An online database search identified RCTs of endovascular stroke therapy published between January 1, 2010, and March

SUBMITTER: Albers GW 

PROVIDER: S-EPMC8314176 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

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