Physician Global Assessment as a Disease Activity Measure for Relapsing Polychondritis.

ABSTRACT:

Objective

Relapsing polychondritis (RP) is a systemic inflammatory disorder of cartilage that lacks validated disease activity measures. Our objective was to test physician global assessment (PhGA), a measure of disease activity commonly used in rheumatic diseases, in a cohort of patients with RP, which has not been done before.

Methods

Adult patients in an observational cohort of RP underwent standardized, comprehensive evaluation at approximately 6-month intervals. PhGA was scored by 3 physicians from the evaluating institution on a scale of 0-10 for each visit. A random subset of 20 visits was scored by 3 independent physicians not affiliated with the evaluating institution. Treatment change between consecutive visits was categorized as increased, decreased, or unchanged.

SUBMITTER: Rose E 

PROVIDER: S-EPMC8339175 | biostudies-literature | 2022 Aug

REPOSITORIES: biostudies-literature