Complexome Profiling: Assembly and Remodeling of Protein Complexes.
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ABSTRACT:
SUBMITTER: Wittig I
PROVIDER: S-EPMC8346016 | biostudies-literature | 2021 Jul
REPOSITORIES: biostudies-literature
Publications
Complexome Profiling: Assembly and Remodeling of Protein Complexes.
Wittig Ilka I Malacarne Pedro Felipe PF
International journal of molecular sciences 20210721 15
Many proteins have been found to operate in a complex with various biomolecules such as proteins, nucleic acids, carbohydrates, or lipids. Protein complexes can be transient, stable or dynamic and their association is controlled under variable cellular conditions. Complexome profiling is a recently developed mass spectrometry-based method that combines mild separation techniques, native gel electrophoresis, and density gradient centrifugation with quantitative mass spectrometry to generate inven ...[more]
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