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Aspergillus niger as a Secondary Metabolite Factory.


ABSTRACT: Aspergillus niger, one of the most common and important fungal species, is ubiquitous in various environments. A. niger isolates possess a large number of cryptic biosynthetic gene clusters (BGCs) and produce various biomolecules as secondary metabolites with a broad spectrum of application fields covering agriculture, food, and pharmaceutical industry. By extensive literature search, this review with a comprehensive summary on biological and chemical aspects of A. niger strains including their sources, BGCs, and secondary metabolites as well as biological properties and biosynthetic pathways is presented. Future perspectives on the discovery of more A. niger-derived functional biomolecules are also provided in this review.

SUBMITTER: Yu R 

PROVIDER: S-EPMC8362661 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature

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<i>Aspergillus niger</i> as a Secondary Metabolite Factory.

Yu Ronglu R   Liu Jia J   Wang Yi Y   Wang Hong H   Zhang Huawei H  

Frontiers in chemistry 20210730


<i>Aspergillus niger</i>, one of the most common and important fungal species, is ubiquitous in various environments. <i>A. niger</i> isolates possess a large number of cryptic biosynthetic gene clusters (BGCs) and produce various biomolecules as secondary metabolites with a broad spectrum of application fields covering agriculture, food, and pharmaceutical industry. By extensive literature search, this review with a comprehensive summary on biological and chemical aspects of <i>A. niger</i> str  ...[more]

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2024-10-01 | GSE241846 | GEO