Surface kinematic and depth-resolved analysis of human vocal folds in vivo during phonation using optical coherence tomography.

ABSTRACT:

Significance

The human vocal fold (VF) oscillates in multiple vectors and consists of distinct layers with varying viscoelastic properties that contribute to the mucosal wave. Office-based and operative laryngeal endoscopy are limited to diagnostic evaluation of the VF epithelial surface only and are restricted to axial-plane characterization of the horizontal mucosal wave. As such, understanding of the biomechanics of human VF motion remains limited.

Aim

Optical coherence tomography (OCT) is a micrometer-resolution, high-speed endoscopic imaging modality which acquires cross-sectional images of tissue. Our study aimed to leverage OCT technology and develop quantitative methods for analyzing the anatomy and kinematics of in vivo VF motion in the coronal plane.

Approach

SUBMITTER: Sharma GK 

PROVIDER: S-EPMC8374544 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature