Impact of septal myectomy on diastolic function in patients with obstructive hypertrophic cardiomyopathy.

ABSTRACT:

Background

The impact of septal myectomy on diastolic function in patients with obstructive hypertrophic cardiomyopathy is not well studied.

Methods

A transcatheter hemodynamic study was performed before and 3 to 6 months after septal myectomy in 12 patients with obstructive hypertrophic cardiomyopathy (HCM).

Results

Postoperative hemodynamic studies were done 4.4±1.2 months after myectomy. The left ventricular outflow tract peak-to-peak gradient decreased from 83.2±43.3 mmHg preoperatively to 11.6±4.3 mmHg after myectomy (P<0.00). The left ventricular diastolic time constant (Tau) was 64.2±26.1 ms before surgery and 42.2±15.7 ms postoperatively (P=0.029). The average left atrial pressure (LAP) decreased from 20.2±7.0 to 12.1±4.5 mmHg after myectomy (P=0.008). Pulmonar

SUBMITTER: Yang Q 

PROVIDER: S-EPMC8411175 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature