Intravenous Immunoglobulin Therapy in Livedoid Vasculopathy: Retrospective Observation of Clinical Outcome and Patient's Activity Level.

ABSTRACT:

Background

Livedoid vasculopathy (LV) is a rare disease characterized by livedo racemosa, atrophie blanche, ulcerations, and severe pain. Low molecular weight heparins and rivaroxaban can be used in LV-patients. In addition, intravenous immunoglobulins (IVIG) have been described as treatment-option.

Objectives

Objective was to investigate the therapeutic effect of IVIG on ulcer, pain and restrictions in daily life.

Methods

Thirty-two LV-patients who received IVIG at the Department of Dermatology Tübingen between 01/2014 and 06/2019 were identified. Twenty-five of these patients were available for further follow up and were included in the study. Patients were interviewed using a questionnaire focusing on the course of the disease, symptoms, and subjective response to

SUBMITTER: Kofler K 

PROVIDER: S-EPMC8474298 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature