Development and validation of a nomogram model for early postoperative hyperlactatemia in patients undergoing cardiac surgery.

ABSTRACT:

Background

Postoperative hyperlactatemia (POHL) is common in patients undergoing cardiac surgery, associated with adverse outcomes. The aim of this study was to identify predictors for POHL after cardiac surgery and to develop and validate a predictive model.

Methods

Adult patients who underwent open heart surgery at our institution between 2016 and 2019 were retrospectively included. The patients were randomly divided into training and validation groups at a 2:1 ratio. Multivariate logistic regression was performed to identify independent predictors for POHL in the training set. A nomogram was then constructed and was validated in the validation set.

Results

POHL developed in 713 of the 5,323 patients (13.4%). The mortality rate was higher in patients with POHL compa

SUBMITTER: Wang S 

PROVIDER: S-EPMC8482329 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature