Pesticide use and kidney function among farmers in the Biomarkers of Exposure and Effect in Agriculture study.

ABSTRACT:

Background

Pesticides have been reported to be associated with malignant and non-malignant kidney disease. Few studies have examined the relationship between individual pesticides and kidney dysfunction.

Objective

We evaluated the associations of pesticide use with measured kidney function among male pesticide applicators in the Biomarkers of Exposure and Effect in Agriculture (BEEA) study, a subcohort in the Agricultural Health Study.

Methods

Serum creatinine was measured in 1545 BEEA participants and estimated glomerular filtration rate (eGFR) was calculated with the chronic kidney disease epidemiology collaboration (CKD-EPI) equation. Using reported information on lifetime use of 41 pesticides, multivariable linear and logistic regression was used to examine associ

SUBMITTER: Shearer JJ 

PROVIDER: S-EPMC8489787 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature