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Application of various surgical techniques in liver transplantation: a retrospective study.


ABSTRACT:

Background

Surgical techniques of liver transplantation have continually evolved and have been modified. We retrospectively analyzed a single-center case series and compared the advantages and disadvantages of each method.

Methods

Six-hundred and seventy-four recipients' perioperative data were assessed and analyzed stratified by different surgical technics [modified classic (MC), modified piggyback (MPB) and classic piggyback (CPB)].

Results

MELD score and Child-Pugh scores was significantly higher in CPB groups (P=0.008 and 0.003, respectively). Anhepatic time in MPB group was longer than those in CPB group (P<0.05). The operation duration in MPB group was significantly longer than those in MC group and CPB group (P=0.003). Three patients had outflow obstruction (P=0.035). The overall survival in MPB group were better than those in MC group and CPB group in general comparison (P<0.001). In patients with preoperative creatine >120 µmol/L, the overall survival in MC group was worst (P<0.001). In patients with a high MELD score (>24), the overall survival in MPB group tended to be the best (P<0.001).

Conclusions

The advantages and disadvantages are different for these three surgical techniques. A reasonable operation technique should be adopted considering the patient's unique condition to ensure the stability of hemodynamics.

SUBMITTER: Chen Z 

PROVIDER: S-EPMC8506559 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature

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Publications

Application of various surgical techniques in liver transplantation: a retrospective study.

Chen Zhitao Z   Ju Weiqiang W   Chen Chuanbao C   Wang Tielong T   Yu Jia J   Hong Xitao X   Dong Yuqi Y   Chen Maogen M   He Xiaoshun X  

Annals of translational medicine 20210901 17


<h4>Background</h4>Surgical techniques of liver transplantation have continually evolved and have been modified. We retrospectively analyzed a single-center case series and compared the advantages and disadvantages of each method.<h4>Methods</h4>Six-hundred and seventy-four recipients' perioperative data were assessed and analyzed stratified by different surgical technics [modified classic (MC), modified piggyback (MPB) and classic piggyback (CPB)].<h4>Results</h4>MELD score and Child-Pugh score  ...[more]

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