Contrasting contributions of anhedonia to obsessive-compulsive, hoarding, and post-traumatic stress disorders.

ABSTRACT: Anhedonia is a transdiagnostic construct that can occur independent of other symptoms of depression; its role in neuropsychiatric disorders that are not primarily affective, such as obsessive compulsive disorder (OCD), hoarding disorder (HD), and post-traumatic stress disorder (PTSD) has received limited attention. This paper addresses this gap. First, the data revealed a positive contribution of anhedonia, beyond the effects of general depression, to symptom severity in OCD but not in HD or PTSD. Second, anhedonia was operationalized as a reduced sensitivity to rewards, which allowed employing the value based decision making framework to investigate effects of anhedonia on reward-related behavioral outcomes, such as increased risk aversion and increased difficulty of making value-based ch

SUBMITTER: Pushkarskaya H 

PROVIDER: S-EPMC8549853 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature