18F-Fludeoxyglucose-Positron Emission Tomography/Computed Tomography and Laparoscopy for Staging of Locally Advanced Gastric Cancer: A Multicenter Prospective Dutch Cohort Study (PLASTIC).

ABSTRACT:

Importance

The optimal staging for gastric cancer remains a matter of debate.

Objective

To evaluate the value of 18F-fludeoxyglucose-positron emission tomography with computed tomography (FDG-PET/CT) and staging laparoscopy (SL) in addition to initial staging by means of gastroscopy and CT in patients with locally advanced gastric cancer.

Design, setting, and participants

This multicenter prospective, observational cohort study included 394 patients with locally advanced, clinically curable gastric adenocarcinoma (≥cT3 and/or N+, M0 category based on CT) between August 1, 2017, and February 1, 2020.

Exposures

All patients underwent an FDG-PET/CT and/or SL in addition to initial staging.

Main outcomes and measures

The primary outcome was the number of pat

SUBMITTER: Gertsen EC 

PROVIDER: S-EPMC8552113 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature