Quantitative EEG During Critical Illness Correlates with Patterns of Long-Term Cognitive Impairment.

ABSTRACT:

Objective

Many intensive care unit (ICU) survivors suffer disabling long-term cognitive impairment (LTCI) after critical illness. We compared EEG characteristics during critical illness with patients' 1-year neuropsychological outcomes.

Methods

We performed a post hoc analysis of patients in the BRAIN-ICU study who had undergone EEG for clinical purposes during admission (n = 10). All survivors underwent formal cognitive assessments at 12-month follow-up. We evaluated EEGs by conventional visual inspection and computed 10 quantitative features. We explored associations between EEG and patterns of LTCI using Wilcoxon rank-sum tests and Spearman's rank correlations.

Results

Of 521 Vanderbilt patients enrolled in the parent study, 24 had EEG recordings during admission.

SUBMITTER: Williams Roberson S 

PROVIDER: S-EPMC8561666 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature