Association of CDH13 Gene Polymorphism and Metabolic Syndrome in Gambian Population.

ABSTRACT:

Background

Polymorphism in CDH13 gene, which encodes for the adiponectin receptor, T-cadherin, is a genetic risk factor associated with metabolic syndrome. CDH13 rs3865188, which is found in the promoter region of the CDH13 gene, has been found to be associated with metabolic syndrome and its traits in Asian and European Caucasian populations. However, to the best of our knowledge, it was yet to be assessed in a Black African population.

Objective

The aim of this study was to investigate the association of CHD13 rs3865188 and metabolic syndrome in a Gambian population.

Methods

It was a genetic association study in a cross-sectional design in 136 Gambian participants. CDH13 rs3865188 was genotyped using PCR master mix and sequencing.

SUBMITTER: Bojang KS 

PROVIDER: S-EPMC8563038 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature