Radiomics based on fluoro-deoxyglucose positron emission tomography predicts liver fibrosis in biopsy-proven MAFLD: a pilot study.

ABSTRACT: Rationale: Since non-invasive tests for prediction of liver fibrosis have a poor diagnostic performance for detecting low levels of fibrosis, it is important to explore the diagnostic capabilities of other non-invasive tests to diagnose low levels of fibrosis. We aimed to evaluate the performance of radiomics based on ¹⁸F-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography (PET) in predicting any liver fibrosis in individuals with biopsy-proven metabolic dysfunction-associated fatty liver disease (MAFLD). Methods: A total of 22 adults with biopsy-confirmed MAFLD, who underwent ¹⁸F-FDG PET/CT, were enrolled in this study. Sixty radiomics features were extracted from whole liver region of interest in ¹⁸F-FDG PET images. Subseque

SUBMITTER: Chen ZW 

PROVIDER: S-EPMC8579290 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature