The role of appendectomy and cholecystectomy in the pathogenesis of colorectal carcinomas.

ABSTRACT:

Background

Several alterations in the gastrointestinal tract which occur after appendectomy or cholecystectomy have been suggested to raise the risk of developing colorectal carcinoma. Given the frequency that these procedures are performed, we sought to determine whether a history of either cholecystectomy or appendectomy increased the risk of future colorectal carcinoma.

Methods

We determined the number of patients with a history of appendectomy and cholecystectomy who developed colorectal carcinoma between January 2018 and February 2021, as well as the latency time between the two diseases. Secondly, we carried out a data-collection spanning 15 years after the primary surgery (January 2005-December 2006).

Results

The post-cholecystectomy state is significantly more

SUBMITTER: Mandi M 

PROVIDER: S-EPMC8599105 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature