Infection with severe fever with thrombocytopenia virus in healthy population: a cohort study in a high endemic region, China.

ABSTRACT:

Background

Severe fever with thrombocytopenia (SFTS) caused by SFTS virus (SFTSV) was a tick-borne hemorrhagic fever that posed significant threat to human health in Eastern Asia. The study was designed to measure the seroprevalence of SFTSV antibody in healthy population residing in a high endemic region.

Methods

A cohort study was performed on healthy residents in Shangcheng County in Xinyang City from April to December in 2018, where the highest SFTS incidence in China was reported. Anti-SFTSV IgG was measured by indirect enzyme-linked immunosorbent assay and neutralizing antibody (NAb) was detected by using PRNT50. The logistic regression models were performed to analyze the variables that were associated with seropositive rates.

Results

Totally 886 individuals we

SUBMITTER: Ye XL 

PROVIDER: S-EPMC8600349 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature