Ontology highlight
ABSTRACT:
SUBMITTER: Lee T
PROVIDER: S-EPMC8614900 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Lee Taesic T Lee Hyunju H The Alzheimer's Disease Neuroimaging Initiative
Biomedicines 20211023 11
Accumulating evidence has suggested a shared pathophysiology between Alzheimer's disease (AD) and cardiovascular disease (CVD). Based on genome-wide transcriptomes, specifically those of blood samples, we identify the shared disease-related signatures between AD and CVD. In addition to gene expressions in blood, the following prior knowledge were utilized to identify several candidate disease-related gene (DRG) sets: protein-protein interactions, transcription factors, disease-gene relationship ...[more]