A Transient Receptor Potential-like Calcium Ion Channel in the Filamentous Fungus Aspergillus nidulans.

ABSTRACT: Transient Receptor Potential (TRP) proteins constitute a superfamily that encodes transmembrane ion channels with highly diverse permeation and gating properties. Filamentous fungi possess putative TRP channel-encoded genes, but their functions remain elusive. Here, we report that a putative TRP-like calcium channel, trpR, in the filamentous fungus Aspergillus nidulans, performs important roles in conidiation and in adapting to cell wall disruption reagents in a high temperature-induced defect-dependent manner, especially under a calcium-limited culture condition. The genetic and functional relationship between TrpR and the previously identified high-affinity calcium channels CchA/MidA indicates that TrpR has an opposite response to CchA/MidA when reacting to cell wall disrup

SUBMITTER: Wang H 

PROVIDER: S-EPMC8618638 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature