Fast acquisition of resting motor threshold with a stimulus-response curve - Possibility or hazard for transcranial magnetic stimulation applications?

ABSTRACT:

Objective

Previous research has suggested that transcranial magnetic stimulation (TMS) related cortical excitability measures could be estimated quickly using stimulus-response curves with short interstimulus intervals (ISIs). Here we evaluated the resting motor threshold (rMT) estimated with these curves.

Methods

Stimulus-response curves were measured with three ISIs: 1.2-2 s, 2-3 s, and 3-4 s. Each curve was formed with 108 stimuli using stimulation intensities ranging from 0.75 to 1.25 times the rMT_guess, which was estimated based on motor evoked potential (MEP) amplitudes of three scout responses.

Results

The ISI did not affect the rMT estimated from the curves (F = 0.235, p = 0.683) or single-trial MEP amplitudes at the group level (F<

SUBMITTER: Kallioniemi E 

PROVIDER: S-EPMC8733273 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature