Treatment in the absence of disease reclassification among men on active surveillance for prostate cancer.

ABSTRACT:

Background

Maintaining men on active surveillance for prostate cancer can be challenging. Although most men who eventually undergo treatment have experienced clinical progression, a smaller subset elects treatment in the absence of disease reclassification. This study sought to understand factors associated with treatment in a large, contemporary, prospective cohort.

Methods

This study identified 1789 men in the Canary Prostate Cancer Active Surveillance Study cohort enrolled as of 2020 with a median follow-up of 5.6 years. Clinical and demographic data as well as information on patient-reported quality of life and urinary symptoms were used in multivariable Cox proportional hazards regression models to identify factors associated with the time to treatment RESULTS: Within 4

SUBMITTER: Kirk PS 

PROVIDER: S-EPMC8738121 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature